Father Lalu Rahadi
Lombok-NTB
What is the difference between emulsion and suspension inactivated vaccines? What are the advantages of each of these forms of vaccine? What are some examples of vaccines of each type? Thank you.
Answer:
Dear. Mr. Lalu Rahadi, thank you for the question. Based on the live nature of the infectious agent contained in the vaccine, vaccine products are divided into 2, namely: active vaccine (active vaccine, live vaccineinactivated vaccines (killed vaccine, inactivated vaccine). The active vaccine contains a weakened virus and serves to bully the formation of immunity of a local nature on the mucosal surface with faster absorption. But it can also form humoral immunity. While the dominant inactivated vaccine serves to bully specific humoral immunity circulating in the blood. Inactivated vaccines contain infectious agents that have been inactivated with the understanding that the microorganism has been killed, but is still immunogenic/able to bully the formation of antibodies. Based on the dosage form, inactivated vaccines can take the form of emulsions and suspensions because they contain adjuvant. Adjuvant is a non-antigenic material / not capable of stimulating the formation of antibodies. The differences between emulsion and suspension inactivated vaccines can be seen in the following table:
The Medion inactivated vaccine contains the virus in the form of an emulsion and suspension. Examples of emulsion inactivated vaccines include Medivac AI, Medivac ND Emulsion, Medivac ND G7B Emulsion, Medivac ND-EDS-IB Emulsion, Medivac ND-IB-Gumboro Emulsion, etc. While the Medion vaccine is in the form of inactive suspensions such as Medivac Coryza B and Medivac Coryza T Suspension.
From the overall Medion vaccine product has several advantages, among others:
- Protective and long-lasting. With an inactivated vaccine, there will be a vaccine depot so that the vaccine will be released slowly so that the antibody titer lasts longer than the active vaccine.
- Practical and efficient. There are combination inactivated vaccines where in 1 vaccine preparation there is more than 1 microorganism, for example: Medivac ND-IB Emulsion, Medivac ND-IB-Gumboro Emulsion. When vaccination programs with adjacent schedules can be done 1 time giving so that it is more practical and efficient, both in terms of cost and energy. In addition, the stress level experienced by chickens will be lighter.
- Adjuvant the vaccine is smooth and homogeneous. Medion inactivated vaccine is made with adjuvant (carrier substances) are fine-particle and homogeneous, thus ensuring a more even distribution of antigens in the vaccine and a more uniform titer of antibodies produced.
- Clear. All vaccines have been approved Quality Control (QC) strict, either based on laboratory test results or directly tested to chickens. The team also conducts research (monitor) the development of the virus and the effectiveness of the use of the vaccine in the field.
- Homologous. Medion, an innovative and quality Indonesian company, as a veterinary drug company trusted by the Indonesian government to produce vaccines. Medion provides vaccines containing viruses / bacteria that are homologous (the same) with those in Indonesia, so it is more suitable to be used to prevent disease attacks in Indonesia. Eg Medivac ND G7B Emulsion containing local nd viruses.
