Mr. Pandu
Banjarmasin
Is it allowed if I inject the emulsion vaccine at the same time as the antibiotic by mixing or dioplossing?
Answer:
Dear. Mr. Pandu in Banjarmasin, thank you for the question that has been sent to the Medion Info team. Mixing / plastering the vaccine with antibiotics is not recommended because it will change the pH, stability, and viscosity of the solution so that it will decrease the potency of the vaccine. This has been proven from the test results conducted by the team Research and Development (R&D) Medion.
According to the results of the test, the vaccine killed mixed with antibiotics pH changes shortly after being mixed and 1 hour post mixing. The optimum pH standard for the vaccine to enter the chicken's body is 6.8 – 7.2 while after mixing, the pH of the solution changes to 4.85 shortly after mixing and then reaches 5.58 at 1 hour after mixing. an inappropriate pH can affect the absorption and performance of the vaccine.
Administration of vaccines mixed with antibiotics can also lead to a decrease in Protectivity in chickens. This is evidenced by the results of a challenge test conducted at 3 weeks after vaccination in broilers. From the test results showed that broilers Vaccine Group mixed with antibiotics have 20% Protectivity. This proves that such mixing lowers the potency of the vaccine. The results of the trial also showed that mixing antibiotics with vaccines can reduce the effectiveness of antibiotics, from bactericidal to bacteriostatic.
Actually, we need to look for the purpose of giving antibiotics during vaccination. Is it because the condition of the chicken is sick so it needs to be treated or to anticipate a reaction post vaccinations are going to happen.
If the administration of antibiotics due to the condition of the chicken is sick so that treatment needs to be done, this needs to be reviewed. Actually, one of the important vaccination conditions we pay attention to is that chickens are healthy. The goal is for the chicken's body, in this case the lymphoid organs, to be able to respond to the presence of the vaccine through the formation of protective antibody titers. When the vaccine is given to sick chickens or an outbreak is happening, it can worsen the condition of the chicken and of course the antibody titer that is formed is not protective. If antibiotics are needed for treatment, they can be given 3-4 days before vaccination, especially if symptoms of respiratory arrest or other bacterial infections appear. It is hoped that with the administration of this antibiotic the concentration of disease seeds in the chicken's body decreases so that the vaccine is able to stimulate the formation of antibody titers optimally.
If the administration of antibiotics aims to reduce the reaction post vaccination, this actually does not need to be done because the vaccine used is a vaccine killed which does not occur reaction post vaccination. Reaction post vaccination reasonably appears as a picture that the chicken's body is responding to the vaccine by forming antibodies. But the reaction post these vaccinations usually appear on active vaccines. When the active vaccine is in the body, the vaccine virus will multiply (multiply) first before going to the lymphoid organs. Well, at the time of this multiplication process will usually appear reaction post vaccination.
